Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 11/20 | 0.71 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803285 | 0.88 | GSR (0.71) | GSRCA2ALDH1A1BCHEMAPT | |
| Bicarbonate SCHEMBL16242334 | 0.85 | GSR (0.61) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL13738690 | 0.84 | GSR (0.59) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL8957312 | 0.84 | GSR (1.00) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL9795224 | 0.84 | GSR (0.59) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL29282915 | 0.84 | GSR (0.59) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL11780937 | 0.84 | GSR (0.59) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL13737852 | 0.84 | GSR (0.59) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL11780669 | 0.82 | GSR (0.60) | GSRCA2ALDH1A1BCHEMAPT | |
| SCHEMBL11875600 | 0.82 | GSR (0.60) | GSRCA2ALDH1A1BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689435-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1996-01-03 | — | — | EP | claimed |
| WO-1994021248-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1994-09-29 | — | — | WO | claimed |
| US-5049694-A | Cardiovascular disorders | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-09-17 | — | — | US | disclosed |
| EP-0223440-B1 | A PROCESS FOR THE PRODUCTION OF HIGH ENERGY MATERIAL | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1991-03-06 | — | — | EP | disclosed |
| US-4985584-A | RING OPENING REACTION WITH N2O4 OR N2O5 | SECRETARY OF STATE FOR DEFENCE (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0359335-A2 | Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance | CEDONA PHARMACEUTICALS B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| EP-0223440-A1 | A process for the production of high energy material | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-05-27 | — | — | EP | disclosed |