SCHEMBL8957664

SCHEMBL8957664

C=C(C)C(=O)OC(C)OC(C)OC(C)OC(C)OC(C)Oc1ccc(C(C)(C)c2ccc(OC(C)OC(C)OC(C)OC(C)OC(C)OC(C)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.36
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 1/20 0.34
KMT2A Q03164 4/20 0.33
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
ELANE P08246 1/20 0.33
POLB P06746 2/20 0.32
PTPN5 P54829 1/20 0.31
ATM Q13315 1/20 0.31
HIF1A Q16665 1/20 0.31
MAPT P10636 1/20 0.30
PARP10 Q53GL7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957662 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL8957744 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL7625139 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL8957644 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL8957788 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL8957729 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL9067297 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL8957777 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL9071095 1.00 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A
SCHEMBL6904850 0.99 AR (0.36) ARKDM4EALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556931-A LENSES TOKUYAMA CORPORATION (JP) 1996-09-17 US claimed
US-5556931-A LENSES TOKUYAMA CORPORATION (JP) 1996-09-17 US disclosed
EP-0691550-A2 Polymerizable composition and organic glass TOKUYAMA CORPORATION (JP) 1996-01-10 EP disclosed