Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625149 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL8957655 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL9067301 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL8957790 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL8957747 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL8957677 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL9071097 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL8957785 | 0.99 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL7622864 | 0.98 | POLB (0.38) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL6904852 | 0.94 | POLB (0.40) | HTTTDP1POLBAPEX1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | claimed |
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0691550-A2 | Polymerizable composition and organic glass | TOKUYAMA CORPORATION (JP) | 1996-01-10 | — | — | EP | disclosed |