Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 18/20 | 0.80 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 3/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18059770 | 0.99 | NQO2 (0.79) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL13928512 | 0.90 | NQO2 (0.76) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL18095067 | 0.87 | NQO2 (0.77) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| Hydrochloric Acid SCHEMBL18059733 | 0.87 | SMARCA2 (0.78) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL8958309 | 0.85 | NQO2 (0.69) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| Hydrochloric Acid SCHEMBL18059764 | 0.85 | NQO2 (0.68) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL13526723 | 0.85 | NQO2 (1.00) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| SCHEMBL18059753 | 0.83 | NQO2 (0.74) | NQO2NQO1 | |
| SCHEMBL753153 | 0.83 | NQO2 (0.66) | NQO2SMARCA2NSD2NQO1KEAP1 | |
| Hydrochloric Acid SCHEMBL20711060 | 0.82 | NQO2 (0.72) | NQO2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016150799-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | Politechnika Gdańska (PL) | 2016-09-29 | — | — | WO | disclosed |
| US-5508289-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | THE UNITED STATES AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-04-16 | — | — | US | disclosed |