SCHEMBL8958533

SCHEMBL8958533

COc1ccc2c(OCc3ccccc3)c(O)c(=O)oc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.59
ACHE P22303 3/20 0.59
NQO1 P15559 1/20 0.55
MAOA P21397 3/20 0.55
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
LMNA P02545 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 4/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
PPARG P37231 1/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957870 0.87 MAOB (0.56) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL8958086 0.84 MAOB (0.55) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL10371693 0.82 KDM4E (0.59) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL8085834 0.82 NQO1 (0.65) MAOBNQO1MAOAKDM4EALDH1A1
SCHEMBL8081637 0.81 NQO1 (0.59) MAOBACHENQO1KDM4EALDH1A1
SCHEMBL26779874 0.81 MAOB (0.79) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL8073822 0.81 HSD17B3 (0.54) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL8073926 0.80 MAOB (0.55) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL28085675 0.80 MAOB (0.65) MAOBACHEMAOAKDM4EALDH1A1
SCHEMBL8495457 0.79 KDM4E (0.54) NQO1MAOAKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646591-B1 3- Or 4-glycosyloxybenzopyran derivative and antiallergic agent containing the derivative as active ingredient DAINIPPON INK & CHEMICALS (JP) 1996-07-31 EP disclosed
US-5525595-A TREATING OR PREVENTING IMMEDIATE OR DELAYED TYPE ALLERGIC DISEASES; LOW TOXICITY DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-06-11 US disclosed
EP-0646591-A1 3- Or 4-glycosyloxybenzopyran derivative and antiallergic agent containing the derivative as active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-04-05 EP disclosed