Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958735 | 1.00 | MEN1 (0.61) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752584 | 0.93 | MEN1 (0.65) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752594 | 0.93 | MEN1 (0.65) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752578 | 0.93 | MEN1 (0.65) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752536 | 0.92 | MEN1 (0.64) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752653 | 0.92 | MEN1 (0.64) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752541 | 0.92 | MEN1 (0.64) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752564 | 0.92 | MEN1 (0.72) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752571 | 0.92 | MEN1 (0.72) | MEN1LMNACYP1A2MAPK1BLM | |
| SCHEMBL8752615 | 0.92 | MEN1 (0.72) | MEN1LMNACYP1A2MAPK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519048-A | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof | MERRELL PHARMACEUTICALS INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5519048-A | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof | MERRELL PHARMACEUTICALS INC. (US) | 1996-05-21 | — | — | US | disclosed |