SCHEMBL8958832

SCHEMBL8958832

CC(C)(C)[Si](C)(C)OOC1C[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1CO

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
ADORA1 P30542 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18927158 0.92 POLB (0.46) POLBADORA1
SCHEMBL9295059 0.92 POLB (0.46) POLBADORA1
SCHEMBL9703679 0.92 POLB (0.46) POLBADORA1
SCHEMBL17860572 0.92 POLB (0.46) POLBADORA1
SCHEMBL31629565 0.88 POLB (0.49) POLBADORA1
SCHEMBL30690961 0.87 SLC29A1 (0.45) POLBADORA1
SCHEMBL21465199 0.87 SLC29A1 (0.45) POLBADORA1
SCHEMBL20534948 0.86 POLB (0.51) POLBADORA1
SCHEMBL11049246 0.86 POLB (0.51) POLBADORA1
SCHEMBL12362206 0.85 POLB (0.61) POLBADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691979-A1 NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM SANOFI (FR) 1996-01-17 EP disclosed
WO-1994022890-A1 NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM STERLING WINTHOP INC. (US) 1994-10-13 WO disclosed