Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958693 | 1.00 | RARB (0.37) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8958733 | 1.00 | RARB (0.37) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8958719 | 1.00 | RARB (0.37) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8958712 | 1.00 | RARB (0.37) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8958581 | 0.99 | RARB (0.35) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8932904 | 0.97 | RARB (0.39) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8932834 | 0.97 | RARB (0.39) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8932855 | 0.97 | RARB (0.39) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8932820 | 0.97 | RARB (0.39) | RARBSPHK1CYP2C9CYP3A4FASN | |
| SCHEMBL8932818 | 0.97 | RARB (0.39) | RARBSPHK1CYP2C9CYP3A4FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |