SCHEMBL8958945

SCHEMBL8958945

CC(C=O)C(=O)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.50
ATM Q13315 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
CDK5 Q00535 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HPGD P15428 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7693073 0.85 ELANE (0.50) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL28814128 0.83 ELANE (0.46) ELANEKMT2AALDH1A1MEN1GAA
SCHEMBL10776089 0.83 ELANE (0.49) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL10062284 0.81 ELANE (0.47) ELANEATML3MBTL1KMT2AALDH1A1
Acetaldehyde SCHEMBL21059045 0.81 ELANE (0.64) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL4316974 0.80 ELANE (0.46) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL28750564 0.80 KMT2A (0.49) KMT2AALDH1A1MEN1GAAALOX15
SCHEMBL2459478 0.79 ELANE (0.56) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL514357 0.79 ELANE (0.72) ELANEATML3MBTL1KMT2AALDH1A1
SCHEMBL29187166 0.79 ELANE (0.72) ELANEATML3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234426-A Core shell nanocapsule or micro-capsule based on hierarchical zeolite 沙特基础工业全球技术公司 2019-09-13 CN disclosed
WO-2014102829-A1 CRYSTALLINE ATROPINE SULFATE Mylan Laboratories Ltd. (IN) 2014-07-03 WO disclosed
CN-1125815-C Method for the synthesis of quinoline derivatives SMITHKLINE BEECHAM CORP (US) 2003-10-29 CN disclosed
CN-1278796-A Method for the synthesis of quinoline derivatives SMITHKLINE BEECHAM CORP (US) 2001-01-03 CN disclosed
US-5519048-A 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof MERRELL PHARMACEUTICALS INC. (US) 1996-05-21 US disclosed