Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120791 | 1.00 | KCNA5 (0.53) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL1143220 | 0.82 | KCNA5 (0.68) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL1143218 | 0.82 | KCNA5 (0.68) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL1152870 | 0.82 | KCNA5 (0.68) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL2763538 | 0.78 | KCNA5 (0.50) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL28827939 | 0.78 | DPP4 (0.50) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL6602135 | 0.76 | KCNA5 (0.39) | KCNA5DPP4F2LMNAMAPK1 | |
| SCHEMBL3054165 | 0.76 | KDM4E (0.44) | KCNA5DPP4F2KDM4ELMNA | |
| SCHEMBL1905925 | 0.74 | AOC3 (0.44) | KCNA5KDM4ELMNAMAPK1ADRA2A | |
| SCHEMBL10777997 | 0.74 | DPP4 (0.46) | KCNA5DPP4F2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208599-A | — | — | None | — | — | JP | disclosed |
| JP-H08208599-A | PROSTAGLANDIN DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1996-08-13 | — | — | JP | disclosed |