Carbamic Acid

Carbamic Acid

SCHEMBL8959472

NC(=O)O.O=c1[nH]cccc1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.79
NAPRT Q6XQN6 1/20 0.53
AURKA O14965 1/20 0.48
AURKB Q96GD4 1/20 0.48
INCENP Q9NQS7 1/20 0.48
KDM4E B2RXH2 5/20 0.46
BLM P54132 3/20 0.46
HSD17B10 Q99714 3/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
RAB9A P51151 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
CYP2C9 P11712 1/20 0.46
PARP15 Q460N3 1/20 0.46
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
TYK2 P29597 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82455 0.89
SCHEMBL692818 0.87
SCHEMBL5596103 0.87
Ammonia Solution, Strong SCHEMBL17005900 0.87
SCHEMBL30482581 0.87
SCHEMBL29127320 0.87
SCHEMBL4286239 0.87
SCHEMBL9517333 0.87
Formamide SCHEMBL28332093 0.83 DAO (0.79) DAONAPRTAURKAAURKBINCENP
Naphthalene SCHEMBL11343213 0.81 DAO (0.83) DAONAPRTAURKAAURKBINCENP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693477-A1 Hydroxypyridonecarboxylic acid amides, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1996-01-24 EP claimed
EP-0584611-B1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF AG (DE) 1996-01-17 EP claimed
EP-0544151-B1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF AG (DE) 1994-06-15 EP claimed
EP-0584611-A1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF Aktiengesellschaft (DE) 1994-03-02 EP claimed
EP-0544151-A1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF Aktiengesellschaft (DE) 1993-06-02 EP claimed
EP-0693477-A1 Hydroxypyridonecarboxylic acid amides, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1996-01-24 EP disclosed
EP-0693477-A1 Hydroxypyridonecarboxylic acid amides, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1996-01-24 EP disclosed
EP-0693477-A1 Hydroxypyridonecarboxylic acid amides, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1996-01-24 EP disclosed
EP-0584611-B1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF AG (DE) 1996-01-17 EP disclosed
EP-0584611-B1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF AG (DE) 1996-01-17 EP disclosed
EP-0544151-B1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF AG (DE) 1994-06-15 EP disclosed
EP-0544151-B1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF AG (DE) 1994-06-15 EP disclosed
EP-0584611-A1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF Aktiengesellschaft (DE) 1994-03-02 EP disclosed
EP-0584611-A1 Heteroaromatically condensed hydroxypyridone carboxamides, their preparation and use BASF Aktiengesellschaft (DE) 1994-03-02 EP disclosed
EP-0544151-A1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF Aktiengesellschaft (DE) 1993-06-02 EP disclosed
EP-0544151-A1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF Aktiengesellschaft (DE) 1993-06-02 EP disclosed
EP-0544151-A1 Hydroxypyridone carboxylic acid amides, their preparation and use as herbicides BASF Aktiengesellschaft (DE) 1993-06-02 EP disclosed