Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959766 | 0.82 | PTGS1 (0.44) | ALDH1A1MMEACES1PR1 | |
| SCHEMBL8959585 | 0.81 | PTGS1 (0.48) | ALDH1A1FFAR4FFAR1S1PR1 | |
| SCHEMBL8959593 | 0.81 | PTGS1 (0.48) | ALDH1A1FFAR4FFAR1S1PR1 | |
| SCHEMBL29074125 | 0.80 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1KMT2AALDH1A1PPARA | |
| SCHEMBL8959763 | 0.80 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PPARAFFAR4MME | |
| SCHEMBL8959834 | 0.76 | PTGS1 (0.48) | CYSLTR2CYSLTR1ALDH1A1FFAR4FFAR1 | |
| SCHEMBL10354176 | 0.75 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1KMT2AALDH1A1PPARA | |
| SCHEMBL825340 | 0.75 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1KMT2AALDH1A1PPARA | |
| SCHEMBL30497412 | 0.75 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1KMT2AALDH1A1PPARA | |
| SCHEMBL7712810 | 0.75 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1ALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |