Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569327 | 0.87 | NOTUM (0.60) | NOTUMHSD17B3AVPR1AKIF11KCNN4 | |
| SCHEMBL5712023 | 0.81 | NOTUM (0.62) | NOTUMHSD17B3KCNN4KCNA3LMNA | |
| SCHEMBL17369318 | 0.81 | NOTUM (0.40) | NOTUMPARK7SMN1; SMN2 | |
| SCHEMBL5712058 | 0.80 | NOTUM (0.60) | NOTUMHSD17B3KCNN4KCNA3GABRA1 | |
| SCHEMBL5712043 | 0.80 | NOTUM (0.60) | NOTUMHSD17B3KCNN4KCNA3MEN1 | |
| SCHEMBL11037023 | 0.80 | NOTUM (0.60) | NOTUMHSD17B3KCNN4KCNA3CYP2D6 | |
| SCHEMBL31394419 | 0.80 | NOTUM (0.60) | NOTUMHSD17B3KCNN4KCNA3MEN1 | |
| SCHEMBL5712014 | 0.79 | NOTUM (0.58) | NOTUMKCNN4KCNA3LMNAALDH1A1 | |
| SCHEMBL5712056 | 0.78 | NOTUM (0.57) | NOTUMHSD17B3CYP11B1CYP11B2LMNA | |
| SCHEMBL1048074 | 0.75 | NOTUM (1.00) | NOTUMHSD17B3KCNN4KCNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| CN-117603121-A | C (sp) of indol-3-one 3 ) Process for preparing-H aminated derivatives | 温州医科大学 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0655440-A2 | 1-Aminoethylindoles | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | NOTUM 4253/4885HSD17B3 4169/4885PARK7 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.