SCHEMBL8960001

SCHEMBL8960001

CC/C=C\Cc1ccc(-c2ccc(-c3ccc(C4CCC(C5CCC(CCCCC)CC5)CC4)cc3F)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
FASN P49327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8933753 0.97 CYP3A4 (0.33) CYP3A4CYP2C9FASN
SCHEMBL8960099 0.94 CYP3A4 (0.31) CYP3A4CYP2C9FASN
SCHEMBL8959793 0.93 CYP3A4 (0.32) CYP3A4CYP2C9FASN
SCHEMBL8959982 0.91 FASN (0.31) CYP3A4CYP2C9FASN
SCHEMBL8934062 0.91 CYP3A4 (0.32) CYP3A4CYP2C9FASN
SCHEMBL8959978 0.90 CYP3A4 (0.32) CYP3A4CYP2C9FASN
SCHEMBL8933863 0.90 CYP3A4 (0.33) CYP3A4CYP2C9FASN
SCHEMBL19985447 0.90 MAPT (0.34) CYP2C9
SCHEMBL19985453 0.90 MAPT (0.34) CYP2C9
SCHEMBL8958717 0.89 CYP3A4 (0.36) CYP3A4CYP2C9FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed