Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.83 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.78 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151096 | 1.00 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL9063641 | 1.00 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL7151100 | 1.00 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| Bromide SCHEMBL11149828 | 0.99 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL9468325 | 0.98 | SLC2A1 (0.79) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL10433624 | 0.97 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL6541565 | 0.92 | ADRB3 (0.72) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL10775030 | 0.92 | SLC2A1 (0.98) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL10775033 | 0.92 | SLC2A1 (0.98) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| Hydrochloric Acid SCHEMBL6539499 | 0.91 | SLC2A1 (0.72) | SLC2A1ADRB2ADRB3ADRB1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519006-A | Phosphonated arylethanolamine compounds with anti-hyperglycemic and/or anti-obesity activity | SMITHKLINE BEECHAM PLC (GB) | 1996-05-21 | — | — | US | claimed |
| US-4622342-A | HYPOGLYCEMIC AGENTS, ANTIOBESITY | BEECHAM GROUP P.L.C. (GB) | 1986-11-11 | — | — | US | claimed |
| EP-0070134-B1 | SECONDARY PHENYL ETHANOL AMINES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | claimed |
| EP-0070134-A1 | Secondary phenyl ethanol amines and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | claimed |
| US-5491134-A | TREATING DIABETES, OBESITY, ACHALASIA, GASTORINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-4622342-A | HYPOGLYCEMIC AGENTS, ANTIOBESITY | BEECHAM GROUP P.L.C. (GB) | 1986-11-11 | — | — | US | disclosed |
| EP-0070134-B1 | SECONDARY PHENYL ETHANOL AMINES AND THEIR PHARMACEUTICAL USE | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | disclosed |
| EP-0070134-A1 | Secondary phenyl ethanol amines and their pharmaceutical use | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |