Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133028 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL29076360 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL136689 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL7733130 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL133404 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL25394046 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL7733446 | 0.95 | CYP1A2 (0.85) | CYP1A2SIGMAR1LSSNAAAEPHX1 | |
| SCHEMBL25392298 | 0.93 | CYP1A2 (0.81) | CYP1A2SIGMAR1HTTLSSNAAA | |
| SCHEMBL25391094 | 0.93 | CYP1A2 (0.81) | CYP1A2SIGMAR1HTTLSSNAAA | |
| SCHEMBL25394210 | 0.93 | CYP1A2 (0.81) | CYP1A2SIGMAR1HTTLSSNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501849-B1 | Fluorinated liquid crystals | THOMSON CSF (FR) | 1996-01-24 | — | — | EP | disclosed |
| US-5298188-A | Chiral compound containing pyran and diphenyl rings and fluorine | THOMSON-CSF (FR) | 1994-03-29 | — | — | US | disclosed |
| EP-0501849-A1 | Fluorinated liquid crystals | THOMSON-CSF (FR) | 1992-09-02 | — | — | EP | disclosed |
| US-4389329-A | Meterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 1983-06-21 | — | — | US | disclosed |
| US-4273929-A | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 1981-06-16 | — | — | US | disclosed |