Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120933 | 0.81 | — | — | |
| SCHEMBL11259701 | 0.81 | TSHR (0.42) | TSHRPTGS2HMGCR | |
| SCHEMBL9547952 | 0.75 | — | — | |
| SCHEMBL2120698 | 0.74 | PTPN7 (0.38) | TSHRPTGS2HMGCR | |
| SCHEMBL6179604 | 0.74 | TSHR (0.36) | TSHRPTGS2 | |
| SCHEMBL28425170 | 0.73 | TSHR (0.39) | TSHRHMGCR | |
| SCHEMBL2119506 | 0.73 | TSHR (0.39) | TSHRPTGS2HMGCR | |
| SCHEMBL18494507 | 0.71 | TSHR (0.42) | TSHRPTGS2HMGCR | |
| SCHEMBL4221274 | 0.71 | — | — | |
| SCHEMBL8001958 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693284-A1 | PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT | TEIJIN LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |