Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365576 | 1.00 | TLR4 (0.34) | TLR4JAK2JAK1CTSLCTSB | |
| SCHEMBL13433647 | 1.00 | TLR4 (0.34) | TLR4JAK2JAK1CTSLCTSB | |
| SCHEMBL31011227 | 1.00 | TLR4 (0.34) | TLR4JAK2JAK1CTSLCTSB | |
| SCHEMBL8961332 | 1.00 | TLR4 (0.34) | TLR4JAK2JAK1CTSLCTSB | |
| SCHEMBL21901314 | 0.94 | TLR4 (0.32) | TLR4 | |
| SCHEMBL21901309 | 0.94 | TLR4 (0.32) | TLR4 | |
| SCHEMBL29273685 | 0.94 | JAK2 (0.33) | JAK2JAK1CTSLCTSBCTSK | |
| SCHEMBL11257958 | 0.94 | JAK2 (0.33) | JAK2JAK1CTSLCTSBCTSK | |
| SCHEMBL11257950 | 0.94 | JAK2 (0.33) | JAK2JAK1CTSLCTSBCTSK | |
| SCHEMBL21901325 | 0.93 | TLR4 (0.31) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398155-B1 | Cyclopropylalkyl or cycloalkenyl compounds, process for their preparation and their use in liquid crystal mixtures | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |