Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795889 | 0.83 | TAAR1 (0.55) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| SCHEMBL9795892 | 0.83 | TAAR1 (0.55) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| Pyrimethanil SCHEMBL20817 | 0.82 | SMN1; SMN2 (0.71) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| Pyrimethanil SCHEMBL10664468 | 0.81 | SMN1; SMN2 (0.69) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| Pyrimethanil SCHEMBL22041985 | 0.81 | SMN1; SMN2 (0.69) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| SCHEMBL9495890 | 0.79 | TAAR1 (0.51) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| SCHEMBL9495894 | 0.79 | TAAR1 (0.51) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| Pyrimethanil SCHEMBL28273473 | 0.77 | SMN1; SMN2 (0.59) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| SCHEMBL12340074 | 0.76 | MAPT (0.71) | TAAR1SMN1; SMN2HTTSLC2A1NPC1 | |
| SCHEMBL8961597 | 0.76 | SRC (0.40) | USP2POLBKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457726-B1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA GEIGY AG (CH) | 1996-02-07 | — | — | EP | disclosed |
| US-5439912-A | Plant fungicide, insecticide, pesticide | CIBA-GEIGY CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0457727-A1 | Pesticides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| EP-0457726-A1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |