Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 19/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963025 | 0.90 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961730 | 0.90 | AVPR2 (0.54) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6964828 | 0.89 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6970491 | 0.88 | AVPR2 (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961739 | 0.88 | AVPR2 (0.60) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6960105 | 0.88 | AVPR2 (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6971296 | 0.87 | AVPR2 (0.65) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961630 | 0.86 | AVPR2 (0.49) | AVPR2AVPR1AOXTR | |
| SCHEMBL6971717 | 0.86 | AVPR2 (0.66) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6966098 | 0.86 | AVPR2 (0.55) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |