SCHEMBL8961686

SCHEMBL8961686

CC(C#N)[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4271106 0.73
SCHEMBL17550902 0.73 TSHR (0.39)
SCHEMBL21648877 0.73
SCHEMBL19419018 0.73
SCHEMBL6746511 0.73
SCHEMBL19419126 0.73
SCHEMBL8756296 0.71 TSHR (0.37)
Iodide SCHEMBL9302279 0.69 TSHR (0.35)
SCHEMBL31415926 0.69
SCHEMBL10586248 0.69 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117440957-B Process for the production of biotin intermediates DSM IP ASSETS B.V. (NL) 2026-05-26 CN claimed
EP-4352064-A1 PROCESS FOR PRODUCING BIOTIN INTERMEDIATE DSM IP Assets B.V. (NL) 2024-04-17 EP claimed
CN-117440957-A Process for the production of biotin intermediates 帝斯曼知识产权资产管理有限公司 2024-01-23 CN claimed
WO-2022257151-A1 PROCESS FOR PRODUCING BIOTIN INTERMEDIATE DSM IP ASSETS B.V. (NL) 2022-12-15 WO claimed
CN-117440957-B Process for the production of biotin intermediates DSM IP ASSETS B.V. (NL) 2026-05-26 CN disclosed
CN-119101067-A Process for the production of biotin intermediates 帝斯曼知识产权资产管理有限公司 2024-12-10 CN disclosed
EP-4352064-A1 PROCESS FOR PRODUCING BIOTIN INTERMEDIATE DSM IP Assets B.V. (NL) 2024-04-17 EP disclosed
CN-117440957-A Process for the production of biotin intermediates 帝斯曼知识产权资产管理有限公司 2024-01-23 CN disclosed
WO-2022257151-A1 PROCESS FOR PRODUCING BIOTIN INTERMEDIATE DSM IP ASSETS B.V. (NL) 2022-12-15 WO disclosed
EP-0424000-B1 Novel silicone polymers, copolymers and block copolymers and a method for their preparation DOW CORNING (US) 1996-02-07 EP disclosed
US-5371147-A Silicone-containing acrylic star polymers, block copolymers and macromonomers PERMEABLE TECHNOLOGIES, INC. (US) 1994-12-06 US disclosed
US-5314960-A Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment PERMEABLE TECHNOLOGIES, INC. (US) 1994-05-24 US disclosed
EP-0068887-B1 \"LIVING\" POLYMERS AND PROCESS FOR THEIR PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-09-24 EP disclosed
US-4581428-A Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-08 US disclosed
EP-0145263-A1 Living polymers and process for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-19 EP disclosed
US-4524196-A Process for preparing \"living\" polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-18 US disclosed
US-4508880-A ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-02 US disclosed
US-4417034-A POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US disclosed
US-4414372-A ADDITION POLYMERS WITH FUNCTIONAL END GROUPS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-08 US disclosed
EP-0068887-A1 \"Living\" polymers and process for their preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed