Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970232 | 0.96 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6959303 | 0.92 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6970362 | 0.91 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6969281 | 0.89 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6967087 | 0.89 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6968185 | 0.88 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6960384 | 0.87 | AVPR2 (0.43) | AVPR1AAVPR1BAVPR2TP53ALDH1A1 | |
| SCHEMBL6971739 | 0.87 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6971642 | 0.86 | AVPR2 (0.50) | AVPR1AAVPR1BAVPR2TP53ALDH1A1 | |
| SCHEMBL9414294 | 0.85 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |