Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 10/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.51 |
| ▸ | OXTR | P30559 | 2/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414288 | 0.93 | AVPR2 (0.52) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL9414281 | 0.92 | AVPR2 (0.49) | AVPR1AAVPR2OXTR | |
| SCHEMBL6964933 | 0.83 | AVPR1A (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL9414292 | 0.83 | AVPR2 (0.58) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6967016 | 0.81 | AVPR1A (0.64) | AVPR1AAVPR2OXTR | |
| SCHEMBL6970366 | 0.81 | AVPR2 (0.53) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6957385 | 0.81 | AVPR1A (0.52) | AVPR1AAVPR2OXTR | |
| SCHEMBL8961731 | 0.78 | AVPR1A (0.52) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL6966646 | 0.77 | AVPR1A (0.56) | AVPR1AAVPR2OXTR | |
| SCHEMBL6957168 | 0.76 | AVPR2 (0.55) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |