Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.56 |
| ▸ | OXTR | P30559 | 1/20 | 0.56 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414268 | 1.00 | AVPR2 (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961678 | 0.92 | AVPR2 (0.64) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961679 | 0.92 | AVPR2 (0.64) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961671 | 0.90 | AVPR2 (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961674 | 0.90 | AVPR2 (0.61) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6989484 | 0.83 | AVPR2 (0.70) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961694 | 0.82 | AVPR2 (0.72) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6972323 | 0.81 | AVPR2 (0.80) | AVPR2AVPR1AOXTR | |
| SCHEMBL7087152 | 0.79 | AVPR2 (0.71) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6955045 | 0.79 | AVPR2 (0.85) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |