Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.57 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.57 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.57 |
| ▸ | MTTP | P55157 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971762 | 0.92 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1BMTTPHTT | |
| SCHEMBL6966416 | 0.90 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1BMTTPACHE | |
| SCHEMBL6963025 | 0.86 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6970821 | 0.85 | AVPR1A (0.57) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6969714 | 0.83 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6958676 | 0.83 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6964270 | 0.83 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6964828 | 0.82 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6965230 | 0.81 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL6969840 | 0.81 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |