⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434982 | 1.00 | — | — | |
| SCHEMBL2432506 | 1.00 | — | — | |
| SCHEMBL43875 | 1.00 | — | — | |
| SCHEMBL574701 | 1.00 | — | — | |
| SCHEMBL574628 | 1.00 | — | — | |
| SCHEMBL2269379 | 1.00 | — | — | |
| Bromide SCHEMBL9149697 | 0.97 | SLC7A5 (0.63) | — | |
| Hydrochloric Acid SCHEMBL7200248 | 0.97 | — | — | |
| Glycine SCHEMBL1000042 | 0.87 | SLC7A5 (0.52) | — | |
| Diaminopropanoic Acid SCHEMBL16057725 | 0.83 | SLC7A5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | THE UNIVERSITY OF HONG KONG (CN) | 2015-05-07 | — | — | US | claimed |
| US-12031167-B2 | Generation of acyl amino acids | MODULAR GENETICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12031167-B2 | Generation of acyl amino acids | MODULAR GENETICS, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3950673-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | Inspirna, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3137447-B1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | RGENIX INC (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10717704-B2 | Inhibitors of creatine transport and uses thereof | RGENIX, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-10717704-B2 | Inhibitors of creatine transport and uses thereof | RGENIX, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190315680-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | INSPIRNA, INC. | 2019-10-17 | — | — | US | disclosed |
| US-20190315680-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | INSPIRNA, INC. | 2019-10-17 | — | — | US | disclosed |
| US-10377699-B2 | Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue | THE UNIVERSITY OF HONG KONG (CN) | 2019-08-13 | — | — | US | disclosed |
| US-10308597-B2 | Inhibitors of creatine transport and uses thereof | RGENIX, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-9970036-B2 | Generation of acyl amino acids | MODULAR GENETICS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9970036-B2 | Generation of acyl amino acids | MODULAR GENETICS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170050924-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | INSPIRNA, INC. | 2017-02-23 | — | — | US | disclosed |
| US-20160076065-A1 | GENERATION OF ACYL AMINO ACIDS | MODULAR GENETICS, INC. | 2016-03-17 | — | — | US | disclosed |
| WO-2015168465-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | RGENIX, INC. (US) | 2015-11-05 | — | — | WO | disclosed |
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | THE UNIVERSITY OF HONG KONG (CN) | 2015-05-07 | — | — | US | disclosed |
| US-5504189-A | HEXAPEPTIDES; ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |