SCHEMBL8962172

SCHEMBL8962172

CCCCCCCC1CCC(C2CCC(c3ccc(-c4ccc(-c5ccc(OCCCC)c(F)c5F)cc4)c(F)c3F)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
SCN9A Q15858 1/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
FPR2 P25090 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962013 0.99 GAA (0.32) GAAMAPTSCN9AALOX5APFEN1
SCHEMBL8961973 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962014 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962197 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962239 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962008 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962009 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962255 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962202 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2
SCHEMBL8962215 0.98 GAA (0.34) GAAMAPTALOX5APFEN1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed