Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.67 |
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962328 | 0.87 | CDC25B (0.77) | CDC25BCDC25AHSD17B10TSHRALDH1A1 | |
| SCHEMBL8439960 | 0.83 | TSHR (0.66) | TSHRCYP2C9ALDH1A1L3MBTL1NR4A1 | |
| SCHEMBL2058645 | 0.81 | CDC25B (1.00) | CDC25BCDC25AHSD17B10ALDH1A1POLB | |
| SCHEMBL3074652 | 0.81 | CDC25B (1.00) | CDC25BCDC25AHSD17B10ALDH1A1POLB | |
| SCHEMBL30403796 | 0.79 | TSHR (0.64) | TSHRCYP2C9ALDH1A1L3MBTL1NR4A1 | |
| SCHEMBL334531 | 0.79 | TSHR (0.64) | TSHRCYP2C9ALDH1A1L3MBTL1NR4A1 | |
| SCHEMBL97298 | 0.78 | TSHR (1.00) | HSD17B10TSHRCYP2C9ALDH1A1POLB | |
| SCHEMBL29904615 | 0.78 | TSHR (1.00) | HSD17B10TSHRCYP2C9ALDH1A1POLB | |
| SCHEMBL64990 | 0.78 | CDC25B (0.79) | CDC25BCDC25AHSD17B10ALDH1A1POLB | |
| SCHEMBL31502517 | 0.78 | TSHR (0.62) | TSHRCYP2C9ALDH1A1L3MBTL1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |