SCHEMBL8962291

SCHEMBL8962291

Cc1ccc(S(=O)(=O)c2ccc(C(=O)O)c(C(=O)O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.60
POLB P06746 2/20 0.60
CTDSP1 Q9GZU7 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
GAA P10253 1/20 0.57
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
PKM P14618 1/20 0.49
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
METAP2 P50579 1/20 0.46
TP53 P04637 1/20 0.45
MCL1 Q07820 2/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999902 0.91 APEX1 (0.70) APEX1POLBCTDSP1L3MBTL1KDM4E
SCHEMBL65212 0.89 APEX1 (0.67) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL1397921 0.89 APEX1 (0.67) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL29364883 0.89 APEX1 (0.67) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL29394064 0.89 APEX1 (0.67) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL15745644 0.88 GAA (0.55) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL268999 0.87 APEX1 (0.65) APEX1POLBCTDSP1L3MBTL1GAA
SCHEMBL5426543 0.85 APEX1 (0.64) APEX1POLBCTDSP1L3MBTL1KDM4E
SCHEMBL29435082 0.85 APEX1 (0.64) APEX1POLBCTDSP1L3MBTL1KDM4E
SCHEMBL10450423 0.85 APEX1 (0.64) APEX1POLBCTDSP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170183527-A1 INK, INK CARTRIDGE, AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2017-06-29 US disclosed
US-5530130-A DYEING PLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed
EP-0639624-A1 Phthaloperinone dyestuffs BAYER AG (DE) 1995-02-22 EP disclosed