Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962495 | 0.95 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962485 | 0.95 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962541 | 0.95 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962520 | 0.95 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962356 | 0.95 | SOAT1 (0.50) | SOAT1 | |
| SCHEMBL8962730 | 0.84 | — | — | |
| SCHEMBL8962709 | 0.78 | SOAT1 (0.48) | SOAT1 | |
| SCHEMBL8962427 | 0.78 | — | — | |
| SCHEMBL8962536 | 0.76 | SOAT1 (0.44) | SOAT1 | |
| SCHEMBL8962453 | 0.73 | MAPT (0.42) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019446-A1 | β-CARBOXY SULFONAMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5491170-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |