Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962799 | 1.00 | CNR1 (0.36) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL8963047 | 0.89 | KCNH2 (0.33) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL8963053 | 0.89 | KCNH2 (0.33) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL8963255 | 0.88 | EP300 (0.32) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL8963262 | 0.88 | EP300 (0.32) | SLC6A2SLC6A4SLC6A3MAOBMAOA | |
| SCHEMBL9450833 | 0.87 | CNR1 (0.32) | CNR1 | |
| SCHEMBL9476640 | 0.87 | SLC6A2 (0.36) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL9476636 | 0.87 | SLC6A2 (0.36) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL9476633 | 0.87 | SLC6A2 (0.36) | CNR1SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL9300289 | 0.85 | HTR2A (0.34) | SLC6A2SLC6A4SLC6A3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |