Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963183 | 0.82 | MAPT (0.58) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8963178 | 0.82 | MAPT (0.58) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL12850507 | 0.77 | MAPT (0.55) | MAPTLMNA | |
| SCHEMBL8630183 | 0.75 | MAPT (0.64) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8630641 | 0.75 | MAPT (0.64) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8634643 | 0.75 | MAPT (0.64) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8627512 | 0.74 | MAPT (0.60) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8708041 | 0.74 | MAPT (0.60) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8631969 | 0.74 | MAPT (0.60) | MAPTPOLBHSD17B10NPC1KDM4E | |
| SCHEMBL8630166 | 0.72 | MAPT (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695308-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024152-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1994-10-27 | — | — | WO | disclosed |