Trolamine

Trolamine

SCHEMBL8963359

CCCCCCCCCCNC(=O)c1ccccc1C(=O)O.OCCN(CCO)CCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.60
TSHR P16473 1/20 0.60
NAAA Q02083 3/20 0.59
HPGD P15428 2/20 0.53
ALDH1A1 P00352 2/20 0.49
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
ALOX15 P16050 2/20 0.48
APP P05067 1/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL9091920 1.00 HTT (0.60) HTTTSHRNAAAHPGDALDH1A1
Trolamine SCHEMBL9089511 1.00 HTT (0.60) HTTTSHRNAAAHPGDALDH1A1
Dimethylaminoethanol SCHEMBL9089538 0.91 HTT (0.58) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL14483849 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL8337568 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL23610316 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL8963414 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL23610299 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL2638598 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1
SCHEMBL11089466 0.89 HTT (0.75) HTTTSHRNAAAHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705591-A2 Cyclic amidocarboxy surfactants, synthesis and use thereof STEPAN COMPANY (US) 1996-04-10 EP disclosed
EP-0486510-B1 CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF STEPAN CO (US) 1996-02-14 EP disclosed
EP-0688601-A1 Cyclic amidocarboxy surfactants, synthesis and use thereof STEPAN COMPANY (US) 1995-12-27 EP disclosed
EP-0486510-A1 CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF. STEPAN CO (US) 1992-05-27 EP disclosed
WO-1991001970-A2 CYCLIC AMIDOCARBOXY SURFACTANTS, SYNTHESIS AND USE THEREOF STEPAN COMPANY (US) 1991-02-21 WO disclosed