Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL8964271

C=O.C=O.OCCOCCO

nearest known ligand 0.77

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.77
MAPK1 P28482 1/20 0.77
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
ALDH1A1 P00352 3/20 0.50
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 1/20 0.33
APP P05067 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL5213209 1.00
Di(Hydroxyethyl)Ether SCHEMBL8330422 0.88 TSHR (0.83) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL8581564 0.88 TSHR (0.83) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL486990 0.88
Di(Hydroxyethyl)Ether SCHEMBL2410410 0.88 TSHR (1.00) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL1462 0.88
Triethylene Glycol SCHEMBL421335 0.85 MEN1 (0.85) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL21384854 0.85 MEN1 (0.85) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL4603067 0.85 MEN1 (0.85) TSHRMAPK1MEN1KMT2AALDH1A1
Hexaethylene Glycol SCHEMBL9719640 0.85 MEN1 (0.85) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006649-B1 METHOD OF MAKING A WATCH CASE AND WATCH OBTAINED BY THIS METHOD ERVIN PIQUEREZ S.A. (CH) 1981-08-12 EP claimed
EP-0348345-B1 Solution stable polyimide resin systems CIBA GEIGY AG (CH) 1996-02-14 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed