Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 6/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HTR6 | P50406 | 3/20 | 0.64 |
| ▸ | HTR1B | P28222 | 3/20 | 0.64 |
| ▸ | SCN1A | P35498 | 2/20 | 0.64 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL896128 | 0.99 | NR2E1 (0.73) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL19440598 | 0.85 | NR2E1 (1.00) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL10737803 | 0.84 | NR2E1 (0.78) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL1298843 | 0.84 | NR2E1 (0.78) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL11742816 | 0.84 | NR2E1 (0.78) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL14070176 | 0.83 | NR2E1 (0.76) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL11226386 | 0.82 | NR2E1 (0.71) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL6018298 | 0.82 | NR2E1 (0.74) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL19031799 | 0.82 | NR2E1 (0.74) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 | |
| SCHEMBL22354430 | 0.81 | NR2E1 (0.74) | NR2E1CYP2D6ADRB2ADRB1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343160-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | BERTEK, INC. | 2014-11-20 | — | — | US | disclosed |
| US-8846093-B2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140243379-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | MYLAN TECHNOLOGIES, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20130018078-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | MYLAN TECHNOLOGIES INC. (US) | 2013-01-17 | — | — | US | disclosed |
| US-20120083535-A1 | ADHESIVE MIXTURE FOR TRANSDERMAL DELIVERY OF HIGHLY PLASTICIZING DRUGS | BERTEK, INC. | 2012-04-05 | — | — | US | disclosed |
| US-20100040690-A1 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. | 2010-02-18 | — | — | US | disclosed |
| US-7638140-B2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-20090041832-A1 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. | 2009-02-12 | — | — | US | disclosed |
| US-7150881-B2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2006-12-19 | — | — | US | disclosed |
| US-7070808-B2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1561461-A2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | MYLAN TECHNOLOGIES, INC. (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20040137046-A1 | such as selegiline and/or the use of protonated forms of various drugs; an adhesive, the drug in protonated form, a nonaqueous solvent that dissolves said drug in either protonated or unprotonated form, and a biocompatible deprotonating agent | MYLAN TECHNOLOGIES, INC. | 2004-07-15 | — | — | US | disclosed |
| US-20020150613-A1 | Patches; sustained release drug delivery | MYLAN TECHNOLOGIES, INC. | 2002-10-17 | — | — | US | disclosed |
| US-20010006628-A1 | Comprising an adhesive, drug in protonated form, a nonaqueous solvent capable of dissolving nonprotonated and protonated forms of the drug, and a biocompatible deprotonating agent to deprotonate the drug without irritating the skin | MYLAN TECHNOLOGIES, INC. | 2001-07-05 | — | — | US | disclosed |
| EP-0887075-A2 | Adhesive mixture for transdermal delivery of highly plasticizing drugs | BERTEK, INC. (US) | 1998-12-30 | — | — | EP | disclosed |