Hexane

Hexane

SCHEMBL8964700

CCCCCC.CCCCCC.NC(O)=S.NC(O)=S

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
SPHK2 Q9NRA0 1/20 0.46
SPHK1 Q9NYA1 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
AKR1B1 P15121 1/20 0.43
DNM1 Q05193 4/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
EPHX1 P07099 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
GPR84 Q9NQS5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL10419469 1.00 TSHR (0.47) TSHRTHRBSPHK2SPHK1SMN1; SMN2
Dodecane SCHEMBL8374269 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Hexane SCHEMBL1286231 0.97 TSHR (0.44) TSHRTHRBSPHK2SPHK1SMN1; SMN2
Octane SCHEMBL6291816 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Tetradecane SCHEMBL7768520 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Tetradecane SCHEMBL8432389 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Heptane SCHEMBL8664516 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Tridecane SCHEMBL6291874 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Octane SCHEMBL28155456 0.97 TSHR (0.53) TSHRTHRBSPHK2SPHK1MEN1
Dodecane SCHEMBL8390187 0.94 TSHR (0.50) TSHRTHRBSPHK2SPHK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104093701-A Separation method ASAHI KASEI CHEMICALS CORP 2014-10-08 CN disclosed
EP-0695291-A1 BISMUTH DITHIOCARBAMATES AND THEIR USE AS ADDITIVE FOR LUBRICANTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-02-07 EP disclosed
WO-1994024100-A1 BISMUTH DITHIOCARBAMATES AND THEIR USE AS ADDITIVE FOR LUBRICANTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-10-27 WO disclosed