Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965136 | 0.88 | PPARG (0.46) | SMN1; SMN2ALDH1A1LMNATHRBCYP1A1 | |
| SCHEMBL9262923 | 0.88 | PPARG (0.46) | SMN1; SMN2ALDH1A1LMNATHRBCYP1A1 | |
| SCHEMBL9259418 | 0.82 | GRM8 (0.38) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8354898 | 0.81 | PTGDR2 (0.45) | CYP1A2PPARGALOX5ALOX5APPTGS1 | |
| SCHEMBL8965101 | 0.80 | PPARG (0.50) | LMNAPPARGPPARAHDAC3HDAC1 | |
| SCHEMBL8965096 | 0.80 | PPARG (0.50) | LMNAPPARGPPARAHDAC3HDAC1 | |
| SCHEMBL8356510 | 0.76 | HDAC3 (0.36) | ALDH1A1PPARGALOX5ALOX5APPTGS1 | |
| SCHEMBL8808705 | 0.73 | PTGIR (0.51) | SMN1; SMN2LMNACFTRSLC6A2SLC6A4 | |
| SCHEMBL8358853 | 0.72 | PPARG (0.44) | ALDH1A1LMNAPPARGPPARAHDAC3 | |
| SCHEMBL8965754 | 0.72 | PPARG (0.44) | ALDH1A1LMNAPPARGPPARAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |