SCHEMBL8965222

SCHEMBL8965222

COc1cc(C(C)=C(C)C(=O)CC(=O)C(C)=C(C)c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
SLC22A6 Q4U2R8 1/20 0.62
SLC22A8 Q8TCC7 1/20 0.62
RAB9A P51151 1/20 0.62
HTT P42858 2/20 0.60
HSD17B2 P37059 2/20 0.56
CYP1A2 P05177 2/20 0.55
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
BLM P54132 1/20 0.55
KDM4E B2RXH2 2/20 0.54
POLB P06746 2/20 0.54
HDAC6 Q9UBN7 2/20 0.54
ALOX5 P09917 3/20 0.50
NFKB1 P19838 2/20 0.50
STAT3 P40763 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
GAA P10253 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965219 1.00 MEN1 (0.62) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL30869298 1.00 MEN1 (0.62) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL10339187 0.80 MEN1 (0.82) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL10339186 0.80 MEN1 (0.82) MEN1KMT2ASLC22A6SLC22A8RAB9A
Apocynin SCHEMBL109514 0.79 MEN1 (0.75) MEN1KMT2ASLC22A6SLC22A8RAB9A
Apocynin SCHEMBL29364797 0.79 MEN1 (0.75) MEN1KMT2ASLC22A6SLC22A8RAB9A
Apocynin SCHEMBL464770 0.79 MEN1 (0.75) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL15842003 0.79 MEN1 (0.74) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL3861897 0.79 MEN1 (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
Methyl Vanillate SCHEMBL25417789 0.78 KMT2A (0.72) MEN1KMT2ASLC22A6SLC22A8RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5334481-A Positive diazo quinone photoresist compositions containing antihalation compound CIBA-GEIGY CORPORATION (US) 1994-08-02 US claimed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP disclosed
US-5399463-A Process of photopatterning a substrate with a positive photoresist composition containing a diazoquinone photosensitizer CIBA-GEIGY CORPORATION (US) 1995-03-21 US disclosed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US disclosed
EP-0200129-B1 POSITIVE PHOTORESIST COMPOSITIONS CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
EP-0200129-A2 Positive photoresist compositions CIBA-GEIGY AG (CH) 1986-11-05 EP disclosed