Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965323 | 1.00 | PTGIR (0.52) | PTGIRPTGDR2POLBSMN1; SMN2KMT2A | |
| SCHEMBL8355223 | 0.82 | PTGIR (0.46) | PTGIRPTGDR2POLBKMT2AMEN1 | |
| SCHEMBL8965712 | 0.82 | PTGIR (0.48) | PTGIRPTGDR2POLBKMT2AMEN1 | |
| SCHEMBL8965715 | 0.82 | PTGIR (0.48) | PTGIRPTGDR2POLBKMT2AMEN1 | |
| SCHEMBL8965328 | 0.82 | PTGIR (0.46) | PTGIRPTGDR2POLBKMT2AMEN1 | |
| SCHEMBL8965101 | 0.78 | PPARG (0.50) | PTGIRPTGDR2KMT2AMEN1 | |
| SCHEMBL8965096 | 0.78 | PPARG (0.50) | PTGIRPTGDR2KMT2AMEN1 | |
| SCHEMBL8358853 | 0.78 | PPARG (0.44) | PTGIRPTGDR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8965754 | 0.78 | PPARG (0.44) | PTGIRPTGDR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8965291 | 0.75 | PTGIR (0.45) | PTGIRPTGDR2POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |