SCHEMBL8965497

SCHEMBL8965497

CCCCCCOc1ccc(-c2ccc(-c3ccc(C4=CCC(C5CCC(CCC)CC5)CC4)c(F)c3)cc2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 2/20 0.32
PTPN1 P18031 1/20 0.30
PTPN6 P29350 1/20 0.30
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965514 1.00 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965532 1.00 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965479 1.00 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965492 0.99 S1PR1 (0.31) PTPN11S1PR1
SCHEMBL8965913 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965730 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965938 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965733 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965897 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1
SCHEMBL8965743 0.97 PTPN11 (0.32) PTPN11PTPN1PTPN6S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed