Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358861 | 1.00 | KMT2A (0.52) | KMT2AMEN1PTGIRL3MBTL1RECQL | |
| SCHEMBL8354920 | 0.85 | KMT2A (0.51) | KMT2AMEN1PTGIRL3MBTL1RECQL | |
| SCHEMBL8354868 | 0.81 | MEN1 (0.52) | KMT2AMEN1PTGIRL3MBTL1PTGDR2 | |
| SCHEMBL8356611 | 0.78 | PPARA (0.60) | KMT2AMEN1PTGIRLMNAPPARG | |
| SCHEMBL8356514 | 0.78 | PPARA (0.51) | KMT2AMEN1PPARGPPARAGAA | |
| SCHEMBL8356517 | 0.78 | PPARA (0.51) | KMT2AMEN1PPARGPPARAGAA | |
| SCHEMBL8358858 | 0.77 | PTGIR (0.55) | KMT2AMEN1PTGIRPTGDR2PPARG | |
| SCHEMBL8358859 | 0.77 | PTGIR (0.55) | KMT2AMEN1PTGIRPTGDR2PPARG | |
| SCHEMBL8350669 | 0.75 | PTGIR (0.81) | KMT2AMEN1PTGIRL3MBTL1PTGDR2 | |
| SCHEMBL8350671 | 0.75 | PTGIR (0.81) | KMT2AMEN1PTGIRL3MBTL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |