Triaziquone

Triaziquone

SCHEMBL8966149

CCCC(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.44
TTR P02766 1/20 0.44
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MAPT P10636 3/20 0.36
TP53 P04637 1/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
DNMT1 P26358 1/20 0.35
USP2 O75604 1/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11740964 0.97 NSD2 (0.42) NSD2TTRFFAR3HDAC3HDAC1
Triaziquone SCHEMBL4299467 0.91 DNMT1 (0.39) NSD2TTRMAPTTP53STAT3
Triaziquone SCHEMBL8966183 0.90 AKR1B1 (0.44) ALDH1A1
Triaziquone SCHEMBL20544204 0.89 PPARG (0.46) ALDH1A1
Triaziquone SCHEMBL9016942 0.89 PPARG (0.46) ALDH1A1
Triaziquone SCHEMBL2341476 0.89 PPARG (0.46) ALDH1A1
Palmitic Acid SCHEMBL2321669 0.89 PPARG (0.46) ALDH1A1
Triaziquone SCHEMBL8966034 0.88 PTGS1 (0.37) NSD2TTRMAPTTP53STAT3
Triaziquone SCHEMBL9390192 0.88 PPARG (0.45) ALDH1A1
Triaziquone SCHEMBL11744543 0.86 PPARG (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5589104-A Electrophoresis separation gel and a method for preparing an electrophoresis separation gel BAMBECK GREGORY S (US) 1996-12-31 US disclosed