Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 18/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524349 | 0.94 | ESR1 (0.88) | ESR1ESR2HRH3 | |
| SCHEMBL8966114 | 0.93 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL8610437 | 0.93 | ESR1 (0.86) | ESR1ESR2HRH3 | |
| SCHEMBL7524102 | 0.93 | ESR1 (0.87) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7523890 | 0.92 | ESR1 (0.86) | ESR1ESR2 | |
| SCHEMBL7525411 | 0.92 | ESR1 (0.85) | ESR1ESR2 | |
| SCHEMBL8966130 | 0.90 | ESR1 (0.86) | ESR1ESR2 | |
| SCHEMBL8966174 | 0.89 | ESR1 (0.80) | ESR1ESR2HRH3 | |
| SCHEMBL7531774 | 0.89 | ESR1 (0.80) | ESR1ESR2HRH3 | |
| SCHEMBL7529579 | 0.88 | ESR1 (0.80) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524742-B1 | Benzo(a)fluorene compounds | LILLY CO ELI (US) | 1996-02-28 | — | — | EP | disclosed |
| EP-0524742-A2 | Benzo(a)fluorene compounds | ELI LILLY AND COMPANY (US) | 1993-01-27 | — | — | EP | disclosed |
| US-5147880-A | Estrogenic and antiestrogenic activity | ELI LILLY AND COMPANY (US) | 1992-09-15 | — | — | US | disclosed |