Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Triaziquone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL2313084 | 0.83 | PDE4A (0.30) | PDE4A | |
| Edetic Acid SCHEMBL3799435 | 0.77 | — | — | |
| Triaziquone SCHEMBL8303 | 0.73 | DNMT1 (0.48) | LMNADNMT1 | |
| Triaziquone SCHEMBL6387848 | 0.73 | MAPT (0.41) | LMNADNMT1 | |
| Triaziquone SCHEMBL10414999 | 0.73 | MAPT (0.41) | LMNADNMT1 | |
| Triaziquone SCHEMBL1538515 | 0.72 | DNMT1 (0.47) | LMNADNMT1 | |
| Triaziquone SCHEMBL7738777 | 0.72 | DNMT1 (0.47) | LMNADNMT1 | |
| Triaziquone SCHEMBL8482641 | 0.72 | DNMT1 (0.47) | LMNADNMT1 | |
| Gluconic Acid SCHEMBL27479225 | 0.70 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1 | |
| Gluconic Acid SCHEMBL15339348 | 0.70 | PDE4A (1.00) | PDE4ALMNAUSP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589104-A | Electrophoresis separation gel and a method for preparing an electrophoresis separation gel | BAMBECK GREGORY S (US) | 1996-12-31 | — | — | US | disclosed |