SCHEMBL8966569

SCHEMBL8966569

BOc1cccc(F)c1F

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.50
SLC6A4 P31645 6/20 0.50
SLC6A3 Q01959 5/20 0.50
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
BCHE P06276 1/20 0.41
TRPA1 O75762 1/20 0.39
HTR1A P08908 2/20 0.36
NFE2L2 Q16236 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
RHEB Q15382 1/20 0.33
HRH1 P35367 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28887844 0.80
SCHEMBL1547396 0.79 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL29387155 0.79 CA1 (0.50) SLC6A2SLC6A4SLC6A3BCHETRPA1
SCHEMBL196734 0.79 CA1 (0.50) SLC6A2SLC6A4SLC6A3BCHETRPA1
SCHEMBL28943454 0.79 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL522189 0.77 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL20594452 0.77 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL4343861 0.77 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL23588427 0.75 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL1401600 0.75 MPL (0.46) SLC6A2SLC6A4SLC6A3CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed