Fluoride

Fluoride

SCHEMBL8966802

F.F.F.Fc1ccccc1Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
LMNA P02545 1/20 0.53
TAAR1 Q96RJ0 2/20 0.44
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.41
ACHE P22303 1/20 0.41
CYP1A2 P05177 5/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
PLA2G1B P04054 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP2A13 Q16696 1/20 0.38
CYP2A6 P11509 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL19837704 1.00 TSHR (0.53) TSHRLMNATAAR1GAAALDH1A1
SCHEMBL168042 0.97
SCHEMBL29591443 0.97
Nitrogen SCHEMBL9740678 0.94 TSHR (0.47) TSHRLMNATAAR1GAAALDH1A1
Hydrogen Sulfide SCHEMBL28293696 0.94
Phosphine SCHEMBL17580267 0.94
Bromide SCHEMBL15754374 0.94
Water SCHEMBL28152579 0.94
Hydrochloric Acid SCHEMBL7436812 0.91 TSHR (0.50) TSHRLMNATAAR1GAAALDH1A1
Potassium Ion SCHEMBL11774711 0.91 TSHR (0.50) TSHRLMNATAAR1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163230-B2 Process for producing aromatic chlorine compounds ASAHI GLASS CO LTD (JP) 1996-03-06 EP disclosed
EP-0163230-B1 PROCESS FOR PRODUCING AROMATIC CHLORINE COMPOUNDS ASAHI GLASS COMPANY LTD. (JP) 1989-03-29 EP disclosed
EP-0163230-A2 Process for producing aromatic chlorine compounds ASAHI GLASS COMPANY LTD. (JP) 1985-12-04 EP disclosed