SCHEMBL8966840

SCHEMBL8966840

CCCC[Si](NC1CCCCC1)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 10/20 0.37
EPHX2 P34913 2/20 0.36
CNR2 P34972 5/20 0.36
CNR1 P21554 4/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4212425 0.83 EPHX1 (0.39) EPHX1EPHX2MEN1KMT2ASIGMAR1
SCHEMBL4211808 0.81 EPHX1 (0.38) EPHX1EPHX2MEN1KMT2ASIGMAR1
SCHEMBL4217698 0.81 MEN1 (0.39) EPHX1EPHX2MEN1KMT2ASIGMAR1
SCHEMBL4208598 0.80 EPHX1 (0.37) EPHX1EPHX2MEN1KMT2ASIGMAR1
SCHEMBL4207785 0.79 MEN1 (0.38) EPHX1EPHX2MEN1KMT2ASIGMAR1
SCHEMBL4205780 0.78 MEN1 (0.37) EPHX1EPHX2MEN1KMT2A
SCHEMBL1536148 0.72 EPHX1 (0.37) EPHX1EPHX2MEN1KMT2A
SCHEMBL4207124 0.70 EPHX1 (0.36) EPHX1EPHX2MEN1KMT2A
SCHEMBL8966848 0.70 EPHX1 (0.31) EPHX1
SCHEMBL4207177 0.69 EPHX1 (0.34) EPHX1EPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696608-B1 Organosilane and organopolysiloxane radical initiators and macromonomers and graft-copolymers prepared therefrom WACKER CHEMIE GMBH (DE) 1996-12-11 EP disclosed
US-5548070-A Organosilicon compounds having triazene groups WACKER-CHEMIE GMBH (DE) 1996-08-20 US disclosed
EP-0696608-A1 Organosilane and organopolysiloxane radical initiators and macromonomers and greft-copolymers prepared therefrom Wacker-Chemie GmbH (DE) 1996-02-14 EP disclosed
EP-0635534-B1 Organosilicon compounds with triazene units WACKER CHEMIE GMBH (DE) 1995-12-06 EP disclosed
EP-0635534-A1 Organosilicon compounds with triazene units Wacker-Chemie GmbH (DE) 1995-01-25 EP disclosed