Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.69 |
| ▸ | RARB | P10826 | 1/20 | 0.62 |
| ▸ | RARG | P13631 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | RXRA | P19793 | 4/20 | 0.53 |
| ▸ | RXRB | P28702 | 4/20 | 0.53 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36693 | 0.88 | SRD5A2 (0.87) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL4577946 | 0.87 | SRD5A2 (0.67) | SRD5A2RARBRARGNR1H4EPHX2 | |
| Hydrochloric Acid SCHEMBL1017064 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL205291 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL4888416 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| Ammonia Solution, Strong SCHEMBL3842685 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL9120613 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL2778034 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| SCHEMBL592353 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 | |
| Methane SCHEMBL10959139 | 0.86 | SRD5A2 (0.83) | SRD5A2RARBRARGNR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8067655-A | — | — | None | — | — | JP | disclosed |
| JP-H0867655-A | NEW P-TERT BUTYLBENZOIC ACID ESTER | FUSO KAGAKU KOGYO KK | 1996-03-12 | — | — | JP | disclosed |