Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 14/20 | 0.58 |
| ▸ | PRKCA | P17252 | 8/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 12/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967456 | 0.89 | PRKCQ (0.72) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8967362 | 0.85 | PRKCQ (0.55) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8966817 | 0.85 | PRKCQ (0.62) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8967517 | 0.85 | PRKCQ (0.60) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8966809 | 0.84 | PRKCQ (0.64) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8967599 | 0.84 | PRKCQ (0.56) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8966638 | 0.84 | PRKCQ (0.71) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL9012757 | 0.84 | PRKCQ (0.82) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8968131 | 0.84 | PRKCQ (0.55) | PRKCQPRKCAPRKCDPRKCBFLT3 | |
| SCHEMBL8966788 | 0.84 | PRKCQ (0.57) | PRKCQPRKCAPRKCDPRKCBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-07 | — | — | US | disclosed |
| US-8188071-B2 | Amino substituted pyridines as potent kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221334-A1 | KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K6 | PRKCQ 38/4885PRKCA 25/4885PRKCD 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.