Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059932 | 0.96 | KMT2A (0.67) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL31146674 | 0.94 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL26103059 | 0.94 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL2059951 | 0.94 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL30158972 | 0.94 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4HPGD | |
| Ethylenediamine SCHEMBL8380520 | 0.89 | KMT2A (0.57) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL9483307 | 0.85 | MAPT (0.48) | KMT2AMAPTMEN1CYP3A4HPGD | |
| Dibenzoylmethane SCHEMBL8074961 | 0.85 | KMT2A (0.63) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL8074905 | 0.85 | KMT2A (0.57) | KMT2AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL1977011 | 0.83 | KMT2A (0.80) | KMT2AMAPTMEN1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5520922-A | GLASS IONOMERS OF ALUMINUM FLUOROSILICATE AND POLYMERIC POLYACID | THERA PATENT GMBH & CO. KG, GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1996-05-28 | — | — | US | disclosed |